NAD+ is a dietary supplement that has become extremely popular recently, and is one of the most studied supplements. (1) There are several reasons for that.
Briefly: NAD+ contributes to energy and reduced fatigue, as well as the mental health we may sometimes need support for, for example when we have to perform various everyday tasks. This is a coenzyme that participates in the body's energy metabolism.
NAD+ is created by a form of vitamin B3 called nicotinamide riboside. There are two other forms: nicotinamide and nicotinic acid. But nicotinamide riboside (NR) is the most effective form that is best converted to NAD+ in the body. Many may wonder what the plus (+) stands for, but it simply means that the molecule is positively charged.
There is a mirror image of NAD+ called NADH, it has a hydrogen atom (H) attached to it and is neutral. They basically do the same thing, but with their different charge they do "opposite" things, much like two sides of the same coin. People mostly talk about NAD+ in the health industry and NADH in chemistry. Well, both are equally important. (2).
There are several ways to increase NAD+, including time-restricted eating and exercise while fasting. A supplement with NAD+ may also be helpful. Great research is going on around NAD+. Nicotinamide riboside (NR) has the potential to support energy levels, nervous system and psychological function.
Furthermore, a study published in Nature Communications showed that when all three forms of vitamin B3, niacin, nicotinamide and NR were tested, NR was the most effective at increasing NAD+ levels.
The other forms lead to this as well but have their own properties that are necessary for the body. Nicotinamide riboside, which is a form of niacin, contributes to normal energy metabolism and to reducing fatigue and exhaustion.
It also contributes to the normal functioning of the nervous system and to normal psychological functioning.